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桔皮素分析标准品 Tangeretin

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品牌：	进口
产品型号：	481-53-8
产品规格：	5mg 10mg
起订：	5 mg
供货总量：	100 mg
发货期限：	自买家付款之日起3天内发货
所在地：	上海
有效期至：	长期有效
最后更新：	2023-07-26 11:42
浏览次数：	292

公司基本资料信息

上海惠诚生物科技有限公司
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地址中国上海国际医学园区芙蓉花路118弄2号楼

产品详细说明

Shanghai HuicH Biotech Co.，Ltd.
上海惠诚生物2010年至今专注于食品检测方面的标准品,优势品牌系列:
药物: TRC LGC USP LKT Focus
植提标准品: Extrasynthese PhytoLab Chromadex CaroteNature
糖类: Elicityl TDB Ludger Megazyme Glycarbo
脂类: Nu-Chek Larodan Avanti Matreya
其他: TCI ERM Wako Jackson Cayman laysan
手机微信：17715331663 QQ:2303607288

Description

Tangeretin is a polymethoxy flavonoid isolated from citrus fruits. This compound exhibits a wide variety of health-related benefits, including anti-inflammatory, anti-allergy, anti-diabetic, and anticancer activities. In an in vivo model of skin-base allergic reaction, administration of tangeretin inhibits expression of IL-4 and TNF-alpha as well as inhibiting activation of NF-kB, AP-1, and p38. In both in vitro and in vivo models of diabetes mellitus, tangeretin increased AMP-K phosphorylation and glucose uptake and altered secretion of adipocytokines such as leptin, adiponectin, resistin, IL-6, and MCP-1. Additionally, this compound induced cell cycle arrest and inhibited proliferation of several cancer cell lines. Tangeretin also inhibits osteoclast formation, suggesting potential benefit as a treatment for bone diseases.

Specifications

Cas No.	481-53-8
Product ID	HT0253
Product Name	桔皮素分析标准品Tangeretin
Formula	C₂₀H₂₀O₇
Formula Wt.	372.37
Purity	≥98%
References	Jang SE, Ryu KR, Park SH, et al. Nobiletin and tangeretin ameliorate scratching behavior in mice by inhibiting the action of histamine and the activation of NF-κB, AP-1 and p38. Int Immunopharmacol. 2013 Aug 9;17(3):502-507. PMID: 23938254. Tominari T, Hirata M, Matsumoto C, et al. Polymethoxy flavonoids, nobiletin and tangeretin, prevent lipopolysaccharide-induced inflammatory bone loss in an experimental model for periodontitis. J Pharmacol Sci. 2012;119(4):390-4. PMID: 22850615. Kim MS, Hur HJ, Kwon DY, et al. Tangeretin stimulates glucose uptake via regulation of AMPK signaling pathways in C2C12 myotubes and improves glucose tolerance in high-fat diet-induced obese mice. Mol Cell Endocrinol. 2012 Jul 6;358(1):127-34. PMID: 22476082. Morley KL, Ferguson PJ, Koropatnick J. Tangeretin and nobiletin induce G1 cell cycle arrest but not apoptosis in human breast and colon cancer cells. Cancer Lett. 2007 Jun 18;251(1):168-78. PMID: 17197076.

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