(20R)-人参皂苷Rg2 | CAS:80952-72-3

IC50 Value & Target:

In Vitro: Inhibitory effect of ginsenoside-Rg2(R) on growth of NCI-H1650 cells is detected by MTT and Annexin-V-PI double staining assays. The results show that different concns. of ginsenoside Rg2(R) test solns. can inhibit the growth of NCI-H1650 cells to varying degrees, and the effect presents evident dose-respo nse and time-effect relationships, i.e., the lo nger the action time, the stro nger the inhibitory effect [1].

In Vivo: Havin activity suppressing the proliferation of both C6 and U251 cells. Structure-activity relatio nship anal. suggested that the acetyl group at C-28 for the Aesculus sapo nins and the mo noterpenic acid moiety for the Gleditsia sapo nins could be crit [2]. Rg2(R) investigate the antioxidant and anti-inflammatory effects of Shengmai San (SMS) and its Et acetate ext. (SEa), n-butanol ext. (SBu), and aq. ext. (SWe), and clarify the material ba se of SMS and the roles played by its fractions [3].