(20S)-人参皂苷Rg2 | CAS:52286-74-5

IC50 Value & Target:

In Vitro: Ginsenoside Rg2(S) prevented LPS-mediated increase of VCAM-1 and ICAM-1 ex pression. Ginsenoside Rg2(S) prevented the decrease of IκBα ex pression stimulated with LPS. Moreover, ginsenoside Rg2(S) reduced LPS-mediated THP-1 mo nocyte adhesion to HUVEC, in a concentration-dependent manner [1]. Ginsenoside Rg2(S) acts specifically on heteromeric human nAChRs modulating their desensitization and suggest a possible mechanism by which this sapo nin co ntributes to the multiple therapeutic effects of ginseng [2].

In Vivo: Have no relevant experimental datas.