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当前位置: 首页 » 食品资讯 » 外讯导读 » 欧盟评估转基因米曲霉菌株NZYM-FB生产的内切-1,4-β-木聚糖酶的安全性

欧盟评估转基因米曲霉菌株NZYM-FB生产的内切-1,4-β-木聚糖酶的安全性

放大字体  缩小字体 时间:2024-12-17 10:41 来源:食品伙伴网 作者: 泽夕   
核心提示:2024年12月16日,欧盟食品安全局就一种食品酶内切-1,4-β-木聚糖酶(endo-1,4-β-xylanase)的安全性评价发布意见。
   食品伙伴网讯  2024年12月16日,欧盟食品安全局就一种食品酶内切-1,4-β-木聚糖酶(endo-1,4-β-xylanase)的安全性评价发布意见。
  
  据了解,这种食品酶是由转基因米曲霉菌株NZYM-FB生产的,旨在用于5种食品生产过程。
  
  经过评估,专家小组得出结论,该食品酶在预期的使用条件下不会引起安全问题。部分原文报道如下:
  
  The food enzyme endo-1,4-β-xylanase (4-β-d-xylan xylanohydrolase, EC 3.2.1.8) is produced with the genetically modified Bacillus subtilis strain LMG S-24584 by Puratos NV. In a previous opinion, the Panel noted the presence of recombinant DNA in all food enzyme batches tested. As a follow-up, the applicant changed the manufacturing process of the food enzyme and provided new data. The genetic modifications do not give rise to safety concerns and the production strain fulfils the requirements for the QPS approach to safety assessment. The food enzyme is free from viable cells of the production organism and its DNA. It is intended to be used in the processing of cereals and other grains for the production of baked products. Dietary exposure is estimated to be up to 0.010 mg TOS/kg body weight per day in European populations. As no concerns arising from the microbial source and its genetic modifications or from the manufacturing process have been identified, the Panel considered that toxicological tests were not needed for the assessment of this food enzyme. A search for the homology of the amino acid sequence of the food enzyme to known allergens was made and no match was found. The Panel considered that the risk of allergic reactions upon dietary exposure cannot be excluded, but the likelihood is low. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns, under the intended conditions of use.
  
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日期:2024-12-17
 
 
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