欧盟评估非转基因毛栓菌菌株AE-OR生产的漆酶的安全?/h1>
放大字体缩小字体时间?024-05-20 11:03 来源:食品伙伴网 作者: 泽夕
核心提示?024??7日,欧盟食品安全局就一种漆酶(laccase)的安全性评价发布意见、/div>
   食品伙伴网讯2024??7日, 欧盟食品安全局就一种漆酶(laccase)的安全性评价发布意见
  据了解,这种食品酶是田a href='//www.sqrdapp.com/news/tag_462.html' class='zdbq' title='非转基因相关食品资讯' target='_blank'>非转基因毛栓菌菌株AE-OR生产的,旨在用于六种食品制造过程、/div>
  经过评估,专家小组认为,在预期的使用条件下,不能排除饮食暴露引起过敏反应的风险,但这种可能性被认为很低。根据所提供的数据,评估小组得出结论,这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下:
  The food enzyme laccase (benzenediol:oxygen oxidoreductase; EC 1.10.3.2) is produced with the non-genetically modified Trametes hirsuta strain AE-OR by Amano Enzyme Inc. The food enzyme is free from viable cells of the production organism. It is intended to be used in six food manufacturing processes. Dietary exposure to the food enzymeCtotal organic solids (TOS) was estimated to be up to 0.026 mg TOS/kg body weight (bw) per day in European populations. Genotoxicity tests did not raise a safety concern. The systemic toxicity was assessed by means of a repeated dose 90-day oral toxicity study in rats. The Panel identified a no observed adverse effect level of 862 mg TOS/kg bw per day, the highest dose tested, which when compared with the estimated dietary exposure, resulted in a margin of exposure of at least 33,154. A search for the similarity of the amino acid sequence of the food enzyme to known allergens was made and no match was found. The Panel co nsidered that a risk of allergic reactions by dietary exposure cannot be excluded, but the likelihood is low. ba sed on the data provided, the Panel co ncluded that this food enzyme does not give rise to safety co ncerns under the intended co nditions of use.
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日期9a href="//www.sqrdapp.com/news/2024-05-20.html">2024-05-20
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