经过评估，专家小组认为该添加剂对所有动物物种、消费者和环境是安全的。当通过饲料施用时，被评估的添加剂在满足动物的营养需求方面是有效的。部分原文报道如下：
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of vitamin B12 (cyanocobalamin) produced by fermentation with a non-genetically modified strain of Ensifer adhaerens (CGMCC 21299), when used as a nutritio
nal additive for all animal species. No viable cells or DNA of the production strain were detected in the additive. Therefore, cyanocobalamin produced by fermentation with E. adhaerens CGMCC 21299 does not raise safety co
ncerns as regards to the production strain. The Panel on Additives and Products or Substances used in Animal Feed co
ncluded that cyanocobalamin produced by fermentation with E. adhaerens CGMCC 21299 is co
nsidered safe for all animal species, for the co
nsumers and the environment. Due to the presence of nickel, the additive is co
nsidered a skin and respiratory sensitiser. Inhalation and dermal exposure are co
nsidered a risk. Due to the lack of data, the Panel could not co
nclude on the potential of the additive to be an eye irritant. Cyanocobalamin produced by fermentation with E. adhaerens CGMCC 21299 is effective in meeting animal's nutritio
nal requirements when administered via feed.
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