　　 食品伙伴网讯2024�?�?0日，�?a href='//www.sqrdapp.com/news/tag_1377.html' class='zdbq' title='欧盟食品安全局相关食品资讯' target='_blank'>欧盟食品安全局＇�a href='//www.sqrdapp.com/news/tag_10.html' class='zdbq' title='EFSA相关食品资讯' target='_blank'>EFSA）消息，应欧盟委员会要求，欧盞�a href='//www.sqrdapp.com/news/tag_4566.html' class='zdbq' title='动物相关食品资讯' target='_blank'>动物饲料添加剁�/a>和产品（FEEDAP）研究小组就大肠杆菌CGMCC 7.455生产的L-苏氨酸（L‐threonine）作为所有动物饲料添加剂的安全性和有效性发表科学意见�

　　经过评估，专家小组认为该添加剂对消费者和环境是安全的。在缺乏数据的情况下，专家小组无法就该添加剂作为皮肤、眼睛刺激物或皮肤敏化剂的可能性得出结论。评估中的添加剂被认为是非反刍动物物种氨基酸L-苏氨酸的有效来源。为了使补充的L-苏氨酸对反刍动物和非反刍动物同样有效，需要防止其在瘤胃中降解。部分原文报道如下：

　　Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of the feed additive co nsisting of l-threo nine produced by fermentation with Escherichia coli CGMCC 7.455 when used as a nutritio nal additive in feed and water for drinking for all animal species and categories. The production strain is genetically modified. None of the introduced genetic modifications raised a safety concern. Viable cells of the production strain and its DNA were not detected in the final additive. Therefore, the final product does not give raise to any safety co ncern regarding the genetic modification of the production strain. The use of l-threo nine (�� 98.5%) produced with E. coli CGMCC 7.455 to supplement feed is safe for the target species. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) has co ncerns on the safety of the simultaneous oral administration of l-threo nine via water for drinking and feed due to possible amino acid imbalances and hygienic reasons. The use of l-threo nine produced with E. coli CGMCC 7.455 in animal nutrition raises no safety co ncerns to co nsumers of animal products and to the environment. In the absence of data, the FEEDAP Panel cannot co nclude on the potential of the additive to be irritant to skin or eyes, or on its potential to be a dermal sensitiser. The endotoxin activity in the additive does not pose a risk for the user via inhalation. The additive l-threo nine is regarded as an effective source of the amino acid l-threo nine for all non-ruminant species. In order to be as efficacious in ruminants as in non-ruminants, it should be protected from ruminal degradation.

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