华中农业大学学者在利用多组学手段解析甜瓜对蔓枯病浸染的防御反应中取得新成果

　　Gummy stem blight （GSB）， a widespread disease causing great loss to cucurbit production, has become a major threat to melon cultivation. However, the melon�CGSB interaction remains largely unknown. Here, full-length trans criptome and widely targeted me tabolome were used to investigate the defence respo nses of resistant （PI511089� and susceptible （Payzawat� melon accessions to GSB pathogen infection at 24?h. The biosynthesis of seco ndary me tabolites and MAPK signalling pathway were specifically enriched for differentially expressed genes in PI511890, while carbohydrate me tabolism and amino acid me tabolism were specifically enriched in Payzawat. More than 1000 novel genes were identified and MAPK signalling pathway was specifically enriched for them in PI511890. There were 11?793 alternative splicing events involving in the defence respo nse to GSB. Totally, 910 me tabolites were identified in Payzawat and PI511890, and flavo noids were the dominant me tabolites. Integrated full-length trans criptome and me tabolome analysis showed eriodictyol and oxalic acid were the potential marker me tabolites for GSB resistance in melon. Moreover, posttrans cription regulation was widely involved in the defence respo nse of melon to GSB pathogen infection. These results not o nly improve our understanding on the interaction between melon and GSB, but also facilitate the genetic improvement of melon with GSB resistance.