銆€銆€鎹簡瑙o紝杩欑椋熷搧閰舵槸鐢包a href='//www.sqrdapp.com/news/tag_462.html' class='zdbq' title='闈炶浆鍩哄洜鐩稿叧椋熷搧璧勮' target='_blank'>闈炶浆鍩哄洜
鏇查湁鑿孅/a>鏍狝E-MB鐢熶骇鐨勶紝鏃ㄥ湪鐢ㄤ簬浜旂椋熷搧鍒堕€犺繃绋嬶細鐢熶骇璋冨懗鍒跺墏锛涘姞宸ユ鐗╁拰鐪熻弻琛嶇敓浜у搧浠ョ敓浜ц泲鐧借川姘磋В浜х墿锛涘姞宸ヨ倝鍜岄奔浜у搧浠ョ敓浜ц泲鐧借川姘磋В浜х墿锛涙敼鑹殑鑲夊拰楸间骇鍝佷互鍙婂姞宸ラ叺姣嶅拰閰垫瘝浜у搧銆侟/div>
銆€銆€缁忚繃璇勪及锛屼笓瀹跺皬缁勮涓猴紝鍦ㄩ鏈熺殑浣跨敤鏉′欢涓嬶紝涓嶈兘鎺掗櫎楗鏆撮湶寮曡捣杩囨晱鍙嶅簲鐨勯闄╋紝浣嗚繖绉嶅彲鑳芥€ц璁や负寰堜綆銆傞壌浜庡緱鍑虹殑鏆撮湶鏋侀檺锛屾棤娉曠‘瀹氶鍝侀叾鐨勫畨鍏ㄦ€с€傚洜姝わ紝璇勪及灏忕粍寰楀嚭缁撹锛岃繖绉嶉鍝侀叾鍦ㄩ鏈熶娇鐢ㄦ潯浠朵笅涓嶈兘琚涓烘槸瀹夊叏鐨勩€傞儴鍒嗗師鏂囨姤閬撳涓嬶細
銆€銆€The food enzyme leucyl aminopeptidase (EC 3.4.11.1) is produced with the non-genetically modified Aspergillus sp. strain AE-MB by Amano Enzyme Inc. The food enzyme is co
nsidered free from viable cells of the production organism. It is intended to be used in five food manufacturing processes: processing of dairy products for the production of (1) flavouring preparations; processing of plant- and fungal-derived products for the production of (2) protein hydrolysates; processing of meat and fish products for the production of (3) protein hydrolysates, (4) modified meat and fish products and processing of (5) yeast and yeast products. Dietary exposure to the food enzyme–total organic solids (TOS) was estimated to be up to 2.273 mg TOS/kg body weight (bw) per day in European populations. Genotoxicity tests did not indicate a safety concern. The systemic toxicity was assessed by means of a repeated dose 90-day oral toxicity study in rats. The Panel identified a no observed adverse effect level of 183 mg TOS/kg bw per day. The calculated margin of exposure for each age group was 135 (infants), 81 (toddlers), 83 (children), 109 (adolescents), 160 (adults) and 184 (the elderly). A search for the similarity of the amino acid sequence of the food enzyme to known allergens was made and no matches were found. The Panel co
nsidered that the risk of allergic reactions by dietary exposure cannot be excluded, but the likelihood is low. The safety of the food enzyme could not be established given the derived margins of exposure. Therefore, the Panel co
ncluded that this food enzyme could not be co
nsidered safe under the intended co
nditions of use.
銆€銆€
鏈枃鐢遍鍝佷紮浼寸綉椋熷搧璧勮涓績缂栬緫锛屾湁浠讳綍鐤戦棶锛岃鑱旂郴news@www.sqrdapp.com銆侟/span>