　　 食品伙伴网讯2023�?�?4日，欧盟食品安全局就一种食品酶三酰甗�a href='//www.sqrdapp.com/news/tag_2271.html' class='zdbq' title='油脂相关食品资讯' target='_blank'>油脂肪酶（triacylglycerol lipase）的安全性评价发布意见�

　　据了解，这种食品酶是由非转基因Burkholderia stagnalis 菌株 PL266-QLM生产的，旨在用于奶酪生产的牛奶加工以及通过酯交换作用对脂肪和油的改性中、�/div>

　　经过评估，专家小组认为，在预期的使用条件下，不能排除通过饮食接触引起过敏反应的风险，但这种情况发生的可能性很低。由于存在传播AMR基因的风险，使用这种食品酶被认为是不安全的。部分原文报道如下：

　　The food enzyme triacylglycerol lipase (triacylglycerol acylhydrolase EC 3.1.1.3) is produced with the non-genetically modified Burkholderia stagnalis strain PL266-QLM by Meito Sangyo CO., LTD. The production strain harbours genes co nferring resistance to highly im portant antimicrobials for human and veterinary medicine. The food enzyme is free from viable cells of the production organism, but not of its DNA. Therefore, the food enzyme poses a risk of promoting the spread of antimicrobial resistance (AMR) genes. It is intended to be used in milk processing for cheese production and modification of fats and oils by interesterification. Since residual amounts of total organic solids (TOS) are removed in the downstream processing of the oils, dietary exposure was calculated o nly for the milk processing for cheese production. Dietary exposure to the food enzyme�CTOS was estimated to be up to 0.663 mg TOS/kg body weight (bw) per day in European populations. Genotoxicity tests did not indicate a safety concern. The systemic toxicity was assessed by means of a repeated dose 90-day oral toxicity study in rats. The Panel identified a no observed adverse effect level of 2,756 mg TOS/kg bw per day in males, the highest dose tested, which, when compared with the estimated dietary exposure, resulted in a margin of exposure of at least 4,157. A search for the similarity of the amino acid sequence of the food enzyme to known allergens was made and no match was found. The Panel co nsidered that, under the intended co nditions of use, the risk of allergic reactions by dietary exposure cannot be excluded, but the likelihood is low. As there is a risk of spreading AMR genes, the use of this food enzyme could not be co nsidered safe.

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欧盟评估一种食品酶三酰甘油脂肪酶的安全�?/h1> 时间�?023-03-27 11:45 来源：食品伙伴网 作者： 泽夕

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