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褰撳墠浣嶇疆: 棣栭〉 » 椋熷搧璧勮 » 澶栬瀵艰 » 娆х洘璇勪及杞熀鍥犵背鏇查湁鑿屾牚AR-183鐢熶骇鐨勫唴鍒囧鑱氬崐涔崇硸閱涢吀閰剁殑瀹夊叏鎬�

娆х洘璇勪及杞熀鍥犵背鏇查湁鑿屾牚AR-183鐢熶骇鐨勫唴鍒囧鑱氬崐涔崇硸閱涢吀閰剁殑瀹夊叏鎬�

鏀惧ぇ瀛椾綋  缂╁皬瀛椾綋 鏃堕棿锛�2023-02-28 10:50 鏉ユ簮锛氶鍝佷紮浼寸綉 浣滆€咃細 娉藉   
鏍稿績鎻愮ず锛�2023骞�2鏈�26鏃ワ紝娆х洘椋熷搧瀹夊叏灞€灏变竴绉嶉鍝侀叾鍐呭垏澶氳仛鍗婁钩绯栭啗閰搁叾锛坋ndo-polygalacturonase锛夌殑瀹夊叏鎬ц瘎浠峰彂甯冩剰瑙併€�
 銆€銆€椋熷搧浼欎即缃戣  2023骞�2鏈�26鏃ワ紝娆х洘椋熷搧瀹夊叏灞€灏变竴绉嶉鍝侀叾鍐呭垏澶氳仛鍗婁钩绯�閱涢吀閰讹紙endo-polygalacturonase锛夌殑瀹夊叏鎬ц瘎浠峰彂甯冩剰瑙併€�
 
銆€銆€鎹簡瑙o紝杩欑椋熷搧閰舵槸鐢�杞熀鍥�绫虫洸闇�鑿屾牚AR-183鐢熶骇鐨勶紝鏃ㄥ湪鐢ㄤ簬浜旂椋熷搧鍒堕€犺繃绋嬶細鏋滄眮鐢熶骇涓殑姘存灉鍜岃敩鑿滃姞宸ャ€佹灉姹佷互澶栦骇鍝佺殑姘存灉鍜岃敩鑿滃姞宸ャ€佽憽钀勯厭鍜岃憽钀勯厭閱嬬殑鐢熶骇銆佷綔涓鸿皟鍛冲埗鍓傜殑妞嶇墿鎻愬彇鐗╃殑鐢熶骇浠ュ強鍜栧暋鑴辫剛銆�
 
銆€銆€缁忚繃璇勪及锛屼笓瀹跺皬缁勮涓猴紝鍦ㄩ鏈熺殑浣跨敤鏉′欢涓嬶紝涓嶈兘鎺掗櫎楗鏆撮湶寮曡捣杩囨晱鍙嶅簲鐨勯闄╋紝灏ゅ叾鏄鑺辩矇杩囨晱鐨勪釜浣撱€傛牴鎹墍鎻愪緵鐨勬暟鎹紝灏忕粍寰楀嚭缁撹锛岃繖绉嶉鍝侀叾鍦ㄩ鏈熶娇鐢ㄦ潯浠朵笅涓嶄細寮曡捣瀹夊叏闂銆傞儴鍒嗗師鏂囨姤閬撳涓嬶細
 
銆€銆€The food enzyme endo-polygalacturonase (1→4)-α-d-galacturonan glycanohydrolase EC 3.2.1.15 is produced with the genetically modified Aspergillus oryzae strain AR-183 by AB ENZYMES GmbH. The genetic modifications do not give rise to safety concerns. The food enzyme is free from viable cells of the production organism and its DNA. It is intended to be used in five food manufacturing processes: fruit and vegetable processing for juice production, fruit and vegetable processing for products other than juice, production of wine and wine vinegar, production of plant extracts as flavouring preparations and coffee demucilation. Since residual amounts of total organic solids (TOS) are removed by repeated washing or distillation, dietary exposure to the food enzyme TOS from coffee demucilation and from the production of flavouring extracts was considered not necessary. For the remaining three food processes, dietary exposure was estimated to be up to 0.087 mg TOS/kg body weight (bw) per day in European populations. Genotoxicity tests did not indicate a safety concern. The systemic toxicity was assessed by a repeated dose 90-day oral toxicity study in rats. The Panel identified a no observed adverse effect level of 1,000 mg TOS/kg bw per day, the highest dose tested, which, when compared with the estimated dietary exposure, resulted in a margin of exposure of at least 11,494. A search for the similarity of the amino acid sequence of the food enzyme to known allergens was made and two matches with pollen allergens were found. The Panel considered that, under the intended conditions of use, the risk of allergic reactions upon dietary exposure to this food enzyme, particularly in individuals sensitised to pollen allergens, cannot be excluded. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.
 
銆€銆€鏈枃鐢遍鍝佷紮浼寸綉椋熷搧璧勮涓績缂栬緫锛屾湁浠讳綍鐤戦棶锛岃鑱旂郴news@www.sqrdapp.com銆�
鏃ユ湡锛�2023-02-28
 

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