根据欧盟委员会第396/2005号法规第12章,欧盟食品安全局审查了二噻农的最大残留限量。根据对现有数据的评估,提出了MRL提案,并进行了消费者风险评估。虽然没有发现对消费者的明显风险,但缺少监管框架要求的一些信息。特别要强调的是,代谢物1?-萘醌的毒理学参考值仅是临时的,有待对潜在致突变性做出结论。因此,消费者风险评估仅被认为是指示性的,EFSA提出的一些MRL建议仍需风险管理者进一步考虑。部分原文报道如下:
According to Article 12 of Regulation (EC) No 396/2005, EFSA has reviewed the maximum residue levels (MRLs) currently established at European level for the pesticide dithianon. To assess the occurrence of dithianon residues in plants, processed commodities, rotatio
nal crops and livestock, EFSA co
nsidered the co
nclusions derived in the f
ramework of Commission Regulation (EC) No 33/2008, the MRLs established by the Codex Alimentarius Commission as well as the European authorisations reported by Member States and the UK, including the supporting residues data. Given that a data gap as regards the magnitude of residues of the me
tabolites 1,4-naphthoquinone and phthalic acid was identified in the peer review for dithianon in light of co
nfirmatory data, the toxicological profile of these me
tabolites was also assessed in the f
ramework of the Article 12 MRL review. ba
sed on the assessment of the available data, MRL proposals were derived and a co
nsumer risk assessment was carried out. Although no apparent risk to co
nsumers was identified, some information required by the regulatory f
ramework was missing. In particular, it is highlighted that the toxicological reference values derived for the me
tabolite 1,4-naphthoquinone are provisio
nal only, pending a co
nclusion on the mutagenicity potential. Hence, the co
nsumer risk assessment is co
nsidered indicative o
nly and some MRL proposals derived by EFSA still require further co
nsideration by risk managers.
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