欧盟评估非转基因米曲霉菌株GL 470生产的?半乳糖苷酶的安全?/h1>
放大字体缩小字体时间?022-10-20 09:53 来源:食品伙伴网 作者: 泽夕
核心提示?022?0?9日,欧盟食品安全局就一种?半乳糖苷酶(β-galactosidase)的安全性评价发布意见、/div>
   食品伙伴网讯2022?0?9日, 欧盟食品安全局就一?beta;- 半乳糕/a>苷酶?beta;-galactosidase)的安全性评价发布意见
  据了解,这种食品酶是田a href='//www.sqrdapp.com/news/tag_462.html' class='zdbq' title='非转基因相关食品资讯' target='_blank'>非转基因 米曲霈/a>菌株GL 470生产的,旨在用于牛奶加工中的乳糖水解、发酵乳制品的生产、乳清加工和酶改性乳制品成分的生产、/div>
  经过评估,专家小组认为,在预期的使用条件下,不能排除饮食暴露引起过敏反应的风险,但这种可能性被认为很低。根据所提供的数据,评估小组得出结论,这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下:
  The food enzyme -galactosidase (-d-galactoside galactohydrolase; EC 3.2.1.23) is produced with the non-genetically modified Aspergillus oryzae strain AE-LA by Amano Enzyme Inc. The food enzyme was co nsidered free from viable cells of the production organism. The food enzyme is intended to be used for lactose hydrolysis in milk processing, production of fermented milk products, whey processing and the manufacture of enzyme-modified dairy ingredients. Dietary exposure to the food enzymeCtotal organic solids (TOS) was estimated to be up to 1.651 mg TOS/kg body weight (bw) per day in European populations. Genotoxicity tests did not indicate a safety concern. The systemic toxicity was assessed by means of a repeated dose 90-day oral toxicity study in rats. The Panel identified a no observed adverse effect level of 1,656 mg TOS/kg bw per day, the highest dose tested. This results in a margin of exposure of at least 1,003. A search for similarity of the amino acid sequence of the food enzyme to known allergens was made and no match was found. The Panel co nsidered that, under the intended co nditions of use, the risk of allergic reactions by dietary exposure cannot be excluded, but the likelihood is co nsidered to be low. ba sed on the data provided, the Panel co ncludes that this food enzyme does not give rise to safety co ncerns under the intended co nditions of use.
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日期9a href="//www.sqrdapp.com/news/2022-10-20.html">2022-10-20
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