欧盟评估非转基因Neobacillus sp.菌株AE-LT生产的?半乳糖苷酶的安全?/h1>
放大字体缩小字体时间?022-10-13 10:11 来源:食品伙伴网 作者: 泽夕
核心提示?022?0?2日,欧盟食品安全局就一种?半乳糖苷酶(β-galactosidase)的安全性评价发布意见、/div>
   食品伙伴网讯2022?0?2日, 欧盟食品安全局就一?beta;- 半乳糕/a>苷酶?beta;-galactosidase)的安全性评价发布意见
  据了解,这种食品酶是田a href='//www.sqrdapp.com/news/tag_462.html' class='zdbq' title='非转基因相关食品资讯' target='_blank'>非转基因Neobacillus sp. 菌株AE-LT生产的,旨在用于牛奶加工和低聚半乳糖生产中的乳糖水解、/div>
  经过评估,专家小组认为,在预期的使用条件下,不能排除饮食暴露引起过敏反应的风险,但这种可能性被认为很低。根据所提供的数据,评估小组得出结论,这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下:
  The food enzyme -galactosidase (EC 3.2.1.23) is produced with the non-genetically modified Neobacillus sp. strain AE-LT by Amano Enzyme Inc. The strain is not cytotoxic and does not harbour any known virulence factor or antimicrobial resistance gene. The presence of viable cells of the production strain in the food enzyme could not be excluded, but the likelihood of this being a hazard is co nsidered low. The food enzyme is intended to be used for lactose hydrolysis in milk processing and the manufacture of galacto-oligosaccharides (GOS). The dietary exposure to the food enzymeCtotal organic solids (TOS) was estimated to be up to 2.971 mg TOS/kg body weight (bw) per day in European populations. Genotoxicity tests did not raise a safety concern. The systemic toxicity was assessed by means of a repeated dose 90-day oral toxicity study in rats. The Panel identified a no observed adverse effect level of 1,223 mg TOS/kg bw per day, the highest dose tested, which when compared with the estimated dietary exposure, results in a margin of exposure of at least 412. A search for similarity of the amino acid sequence of the food enzyme to known allergens was made and no match was found. The Panel co nsidered that, under the intended co nditions of use, the risk of allergic reactions by dietary exposure cannot be excluded, but the likelihood for this to occur is low. ba sed on the data provided, the Panel co ncluded that this food enzyme does not give rise to safety co ncerns under the intended co nditions of use.
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日期9a href="//www.sqrdapp.com/news/2022-10-13.html">2022-10-13
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