据了解,该添加剂是由Komagataella phaffii DSM 33574生产的。部分原文报道如下:
Following a request from the European Commission, the EFSA Panel on Additives and Products of Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of the product co
ntaining endo-1,4--xylanase produced by Komagataella phaffii DSM 33574 (Xylamax) as a zootechnical additive in chickens for fattening, chickens reared for laying/breeding, turkeys for fattening, turkeys reared for breeding and minor poultry species for fattening or raised to the point of lay. The production strain is genetically modified. No viable cells nor recombinant DNA of the production strain were detected in the final product. Therefore, the Panel co
ncluded that the additive does not pose any safety co
ncern regarding the production strain. ba
sed on the no observed adverse effect level identified in a subchro
nic oral toxicity study in rats, the Panel co
ncluded that Xylamax is safe for all poultry species for fattening or reared to the point of lay. Co
nsidering the production strain and the results obtained in the genotoxicity studies, the Panel co
ncluded that the additive is safe for the consumers. The Panel also co
ncluded that Xylamax is not irritant to the skin but should be co
nsidered a potential eye irritant and a respiratory sensitiser. No co
nclusions could be drawn on the potential of the additive to cause skin sensitisation. The use of the product as a feed additive is of no co
ncern for the environment. The FEEDAP Panel co
ncluded that the additive has the potential to be efficacious at 10,000 XU/kg feed in chickens for fattening. This co
nclusion was extended/extrapolated to chickens reared for laying/breeding, turkeys for fattening, turkeys reared for breeding and minor poultry species for fattening or raised to the point of lay.
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