　　 食品伙伴网讯2022�?�?8日，欧盟食品安全局就一种内切多聙�a href='//www.sqrdapp.com/news/tag_2554.html' class='zdbq' title='半乳糖相关食品资�? target='_blank'>半乳糕�/a>醛酸酶（endo-polygalacturonase）的安全性评价发布意见�

　　据了解，这种食品酶是由转基因硫球曲霉（Aspergillus luchuensis）菌株FLYSC生产的，旨在用于水果和蔬菜加工中，以生产果汁、�/div>

　　经过评估，专家小组认为，在预期的使用条件下，对于对雪松、草花粉或玉米过敏的个体，不能排除饮食暴露引起过敏和诱发反应的风险。根据所提供的数据，小组得出结论，该食品酶在预期的使用条件下不会引起安全隐患。部分原文报道如下：

　　The food enzyme endo-polygalacturo nase ((1��4)-��-d-galacturo nan glycanohydrolase; EC 2.3.1.15), is produced with the genetically modified Aspergillus luchuensis strain FLYSC by Advanced Enzyme Technologies Ltd. The genetic modifications do not give rise to safety concerns. The food enzyme is co nsidered free from viable cells of the production organism and its DNA. The food enzyme is intended to be used in fruit and vegetable processing for juice production. ba sed on the maximum use level, dietary exposure to the food enzyme�Ctotal organic solids (TOS) was estimated to be up to 0.138 mg TOS/kg body weight (bw) per day in European populations. Genotoxicity tests did not raise a safety concern. The systemic toxicity was assessed by means of a repeated dose 90-day oral toxicity study in rats. The Panel identified a no observed adverse effect level of 800 mg TOS/kg bw per day, the highest dose tested, which when compared with the estimated dietary exposure, results in a margin of exposure of at least 5,800. A search for similarity of the amino acid sequence of the food enzyme to known allergens was made and six matches were found. The Panel co nsidered that, under the intended co nditions of use, the risk of allergic sensitisation and elicitation reactions by dietary exposure cannot be excluded for individuals sensitised to cedar or grass pollen or maize. ba sed on the data provided, the Panel co ncluded that this food enzyme does not give rise to safety concerns, under the intended co nditions of use.