经过评估，专家小组认为在动物营养中使用这些菌株对目标物种、消费者和环境是安全的。该添加剂对皮肤和眼睛没有刺激性，也不是皮肤敏化剂。专家小组无法就添加剂显着减少饲料中鼠伤寒沙门氏菌或大肠杆菌生长的功效得出结论。部分原文报道如下：

 

　　Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the preparation of Bacillus subtilis CNCM I-4606, B. subtilis CNCM I-5043, B. subtilis CNCM I-4607 and Lactococcus lactis CNCM I-4609 when used as a technological additive (hygiene condition enhancer) for all animal species. The product is intended for use in compound feeds and feed materials for all animal species at a minimum inclusion level of 1×10⁹ CFU B.subtilis and 1×10⁹ CFU L.lactis per kg or litre. The two bacterial species are considered by EFSA to be eligible for the qualified presumption of safety (QPS) approach. As the identity of the strains has been clearly established and they did not show acquired resistance to antibiotics of human and veterinary importance, the use of these strains in animal nutrition is considered safe for the target species, consumers and the environment. The additive is not irritant to skin and eyes or a skin sensitiser. Given the proteinaceous nature of the active agents, the additive should be considered a respiratory sensitiser. The Panel is not in the position to conclude on the efficacy of the additive to significantly reduce the growth of either Salmonella Typhimurium or Escherichia coli in feed.

 

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