食品伙伴网讯2021??3日,
欧盟食品安全局就一秌a href='//www.sqrdapp.com/news/tag_3954.html' class='zdbq' title='过氧化氢酶相关食品资? target='_blank'>过氧化氢酵/a>(catalase)的安全性评价发布意见、/div>
据了解,这种食品酶是由转基因黑曲霉菌株DP-Azw58生产的,旨在用于鸡蛋加工中、/div>
经过评估,专家小组认为,在预期的使用条件下,不能排除饮食暴露引起过敏和诱发反应的风险,但这种情况发生的可能性很低。根据提供的数据,小组得出结论,该食品酶在预期的使用条件下不会引起安全隐患。部分原文报道如下:
The food enzyme catalase (hydrogen-peroxide:hydrogen-peroxide oxidoreductase; EC 1.11.1.6) is produced with the genetically modified Aspergillus niger strain DP-Azw58 by Danisco US, Inc. The genetic modifications do not give rise to safety concerns. The food enzyme is co
nsidered free from viable cells of the production organism and its DNA. It is intended to be used in egg processing. ba
sed on the maximum use levels, dietary exposure to the food enzymeCtotal organic solids (TOS) was estimated to be up to 1 g TOS/kg body weight (bw) per day in European populations. Genotoxicity tests did not indicate a safety concern. The systemic toxicity was assessed by means of a repeated dose 90-day oral toxicity study in rats. The Panel identified a no observed adverse effect level of 1,288 mg TOS/kg bw per day, the highest dose tested, which when compared with the estimated dietary exposure, results in a margin of exposure of at least 1.3 106. A search for similarity of the amino acid sequence of the food enzyme to known allergens was made and one match was found. The Panel co
nsidered that, under the intended co
nditions of use, the risk of allergic sensitisation and elicitation reactions by dietary exposure cannot be excluded, but the likelihood for this to occur is co
nsidered to be low. ba
sed on the data provided, the Panel co
ncluded that this food enzyme does not give rise to safety co
ncerns under the intended co
nditions of use.
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相关政策解读
日期9a href="//www.sqrdapp.com/news/2021-08-16.html">2021-08-16
地区9/font>欧盟国外
行业9/font>添加剂配斘/font>进出叢/font>
标签9/font>过氧化氢酵/font>食品欧盟食品安全局
科普9/font>过氧化氢酵/font>食品欧盟食品安全局
行业9/font>添加剂配斘/font>进出叢/font>
标签9/font>过氧化氢酵/font>食品欧盟食品安全局
科普9/font>过氧化氢酵/font>食品欧盟食品安全局