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欧盟评估一种长链糖脂作为食品添加剂的安全性

放大字体  缩小字体 时间:2021-06-16 15:53 来源:食品伙伴网 作者: 泽夕   
核心提示:2021年6月14日,据欧盟食品安全局(EFSA)消息,欧盟食品添加剂和调味剂小组( FAF )评估来自匙盖假花耳(Dacryopinax spathularia)的长链糖脂 (long-chain glycolipids )作为食品添加剂的安全性。
   食品伙伴网讯  2021年6月14日,据欧盟食品安全局EFSA)消息,欧盟食品添加剂调味剂小组( FAF )评估来自匙盖假花耳(Dacryopinax spathularia)的长链糖脂 (long-chain glycolipids )作为食品添加剂的安全性。
 
  经过评估,专家小组得出结论,认为来自匙盖假花耳的长链糖脂不会对申请人提议的用途和使用水平产生安全问题。部分原文报道如下:
 
  The EFSA Panel on Food Additives and Flavourings (FAF) provides a scientific opinion on the safety of long-chain glycolipids from Dacryopinax spathularia (also called AM-1) as a food additive. AM-1 is a purified mixture of long-chain glycolipid congeners obtained by fermentation of the edible non-genetically modified fungus Dacryopinax spathularia. AM-1 glycolipids have very low oral bioavailability and overall available toxicology data do not demonstrate any adverse effects of the proposed food additive. Considering the available data set the Panel established an ADI of 10 mg/kg bw per day based on a range of NOAELs between 1,000 and 1,423 mg/kg bw per day (the highest doses tested), from the reproductive and a prenatal developmental toxicity studies in rats and 90-day studies in rat and dog. At the proposed maximum use levels, the exposure estimates ranged at the mean from 0.01 to 1.07 mg/kg bw per day and at the p95 from 0 to 3.1 mg/kg mg/kg bw per day. At the proposed typical use levels, the exposure estimates ranged at the mean from < 0.01 mg/kg bw per day to 0.23 mg/kg bw per day and at the p95 from 0 to 0.64 mg/kg bw per day. The Panel noted that the highest estimate of exposure of 3.1 mg/kg bw per day (in toddlers) is within the established ADI of 10 mg/kg bw per day and concluded that the exposure to long-chain glycolipids from Dacryopinax spathularia does not raise a safety concern at the uses and use levels proposed by the applicant.
 
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日期:2021-06-16
 
 
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