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当前位置: 首页 » 食品资讯 » 外讯导读 » 欧盟评估维生素B12作为所有动物营养添加剂的安全性

欧盟评估维生素B12作为所有动物营养添加剂的安全性

放大字体  缩小字体 时间:2020-12-15 09:32 来源:食品伙伴网 作者: 泽夕   
核心提示:2020年12月14日,据欧盟食品安全局(EFSA)消息,应欧盟委员会要求,欧盟动物饲料添加剂和产品(FEEDAP)研究小组就维生素B12(vitamin B12 )作为所有动物营养添加剂的安全性发表科学意见。
   食品伙伴网讯  2020年12月14日,据欧盟食品安全局EFSA)消息,应欧盟委员会要求,欧盟动物饲料添加剂和产品(FEEDAP)研究小组就维生素B12(vitamin B12 )作为所有动物营养添加剂的安全性发表科学意见。
 
  据了解,该维生素B12是由Ensifer adhaerensCNCM‐I 5541生产的。经过评估,专家小组得出结论,该维生素B12对所有动物物种、消费者和环境都是安全的。申请人没有提供新的证据来促使研究小组重新考虑先前关于用户安全的结论。部分原文报道如下:
 
  The vitamin B12 (in the form of cyanocobalamin) under assessment is produced by fermentation with a genetically modified strain of Ensifer adhaerens and it is intended to be used as a nutritional additive for all animal species. In 2018, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) of EFSA issued an opinion on the safety and efficacy of the product. In that assessment, the Panel could not conclude on the safety of the additive for the target species, consumers and the environment due to uncertainties on the safety of the production strain and the resulting product. Due to high endotoxin content, potential inhalation exposure when handling premixtures and reported irritancy for skin and eyes, the additive was considered to pose a risk to user safety. The applicant provided supplementary data on the identity of the production strain, its susceptibility to antibiotics and toxigenic potential, as well as on the absence of cells and recombinant DNA of the production strain in the final product. The production strain is not expected to produce any toxic compound during fermentation but harbours antimicrobial resistance genes. However, viable cells and recombinant DNA of the strain were not detected in the most concentrated form of the additive. With this new information, the FEEDAP Panel concluded that vitamin B12 produced by E. adhaerensCNCM I‐5541 (identified as SCM 2034 in the previous opinion) is safe for all animal species, the consumers and the environment. The applicant did not provide new evidence that would lead the FEEDAP Panel to reconsider previous conclusions regarding the safety for the user.
 
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日期:2020-12-15
 
 
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