据了解，这种食品酶是由Novozymes A/S公司用转基因地衣芽孢杆菌 Bacillus licheniformis）菌株NZYM-VR生产的，旨在用于油脂的脱胶中。经过评估，专家小组得出结论，这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下：
The food enzyme phospholipase C （phosphatidylcholine cholinephosphohydrolase EC 3.1.4.3 is produced with the genetically modified Bacillus licheniformis strain NZYM ‐VR by Novozymes A/S. The genetic modifications do not give rise to safety concerns. The food enzyme is free from viable cells of the production organism and its DNA . This phospholipase C is intended for use in degumming of fats and oils. The residual amounts of Total Organic Solids （TOS are removed during washing and purification steps applied during degumming. Consequently, no dietary exposure was calculated. Genotoxicity tests did not raise a safety concern. The systemic toxicity was assessed by means of a repeated dose 90‐day oral toxicity study in rats. The Panel identified a No Observed Adverse Effect Level （NOAEL at the highest dose tested of 714 mg TOS /kg body weight （bw per day. Similarity of the amino acid sequence to those of known allergens was searched for and no match was found. The Panel co
nsidered that, under the intended co
nditions of use, the risk of allergic sensitisation and elicitation reactions by dietary exposure cannot be excluded, but the likelihood is co
nsidered to be low. ba
sed on the data provided and the removal of TOS during the degumming of fats and oils, the Panel co
ncluded that this food enzyme does not give rise to safety co
ncerns under the intended co
nditions of use.
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