大豆半纤维素并不会被人体直接吸收,而是通过人与动物肠道微生物的发酵后被人体利用。欧盟专家组开展了老鼠膳食毒理学试验,并未发现不良反应。大豆半纤维素无基因毒性。日常膳食暴露水平基本可以忽略不计。
鉴于这些,欧盟食品安全局专家组认为,按照目前的使用方式将其用作食品添加剂无安全风险,然而建议降低大豆半纤维素中的蛋白残留量,告知消费者潜在的过敏蛋白。
部分原文报道如下:
Following a request from the European Commission, the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) was asked to deliver a scientific opinion on the re-evaluation of soybean hemicellulose (E 426) as a food additive. Soybean hemicellulose is not absorbed intact, but is extensively fermented by the intestinal microflora in animals and humans. No adverse effects were reported in a 90-day dietary toxicity study in rats at the highest doses tested of 2,430 mg/kg body weight (bw) per day for males and 2,910 mg/kg bw per day for females. Furthermore, soybean hemicellulose is not of genotoxic concern.
原文链接:http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2017.4721/full