链格孢霉毒素是真菌产生的一种次级代谢产物,可污染谷物、油籽、果蔬。欧盟食品安全局对四种链格孢霉毒素的慢性膳食暴露风险进行了分析,使用了15563份分析结果,4249份样本(3648份针对格链孢菌醇(AOH),3654份针对交链孢醇单四醚(AME),4168份针对细交链孢菌酮酸(TeA),4093份针对腾毒素(TEN))。分析发现,学步儿童对四种链格孢霉毒素的膳食暴露量最大。
部分原文报道如下:
Alternaria toxins are secondary metabolites produced by fungi that can contaminate cereals, oilseeds, fruits and vegetables. The chronic dietary exposure to four individual Alternaria toxins was estimated using 15,563 analytical results/4,249 samples (3,648 on alternariol (AOH), 3,654 on alternariol monomethyl ether (AME), 4,168 on tenuazonic acid (TeA) and 4,093 on tentoxin (TEN))。 Most of the analytical results were left-censored data (92%), with only 1,290 quantified results (mainly on 'Oilseeds' and 'Grain milling products‘)。 The highest exposure to AOH was estimated in 'Toddlers’, with the mean exposure between 3.8 and 71.6 ng/kg body weight (bw) per day (minimum lower bound–maximum upper bound, (LB–UB)) and the 95th percentile exposure between 11.4 and 270.5 ng/kg bw per day (LB–UB)。
原文链接:http://www.efsa.europa.eu/en/efsajournal/pub/4654