β-环糊精由7个 α-1,4-链接 d-葡糖基构成的环状寡糖。在1996年欧盟专家组将其ADI定为5mg/kg体重/天。欧盟专家组经过再次评估后认为，ADI设定为5mg/kg体重/天仍然合理。然而在现有报道以及使用量的情况下，在品牌忠诚的情况下，所有人群的摄入量会超过ADI数值，婴儿平均值统计（mean percentile）以及所有人群95值统计（95th percentile）的情况除外。

 

    部分原文报道如下：

 

    he EFSA Panel on Food Additives and Nutrient Sources added to Food （ANS） provides a scientific opinion re-evaluating the safety of β-cyclodextrin （E 459） as a food additive. β-Cyclodextrin is a non-reducing cyclic oligosaccharide consisting of seven α-1,4-linked d-glucopyranosyl units. The Scientific Committee on Food （SCF） allocated an acceptable daily intake （ADI） of 5 mg/kg body weight （bw） per day to β-cyclodextrin （E 459） in 1996.

 

    The Panel concluded that, based on the available toxicological database, there is no reason to revise the current ADI of 5 mg/kg bw per day for β-cyclodextrin. based on the available reported use and use levels, the Panel also concluded that the ADI was exceeded in the refined brand-loyal scenario （considered the most relevant scenario） in all population groups except for infants at the mean and in all population groups at the 95th percentile.

 

    原文链接：http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4628/full