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刘学波

浏览：161 来源：西北农林科技大学食品科学与工程学院原文：

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姓名：刘学波	性别：男
民族：汉族	出生年份：1975
最高学历：研究生	学位：博士
西北农林科技大学食品科学与工程学院副院长，入选教育部“新世纪优秀人才计划”、西北农林科技大学“青年学术骨干支持计划”，荣获第四届“杨凌十大杰出青年”称号。　　一、学习情况　　学士东北农业大学食品科学系，哈尔滨，中国　　硕士广岛大学生物圈科学研究科食品卫生学专业，广岛，日本　　博士名古屋大学生命农学研究科食品功能化学专业，名古屋，日本　　二、工作简历　　1997.08－2001.03 在东北农业大学工作；　　2004.05－2005.03 在日本名古屋大学农学部工作研究员；　　2008.03－2008.10 在日本名古屋大学生命农学研究科工作博士后研究员；　　2008.12－至今在西北农林科技大学食品科学与工程学院工作，期间2010年6月任副院长；　　三、研究领域或方向　　营养与功能食品因子，具体为：① 天然食品因子的营养功能性评价及分子机制；② 功能因子体内代谢的化学生物学研究；③ 纳米技术应用于功能食品开发中的分子基础。

　　以第一作者或通讯作者发表SCI论文情况

　　(1) Liu Z., Song G., Zou C., Liu G., Wu W., Yuan L. and Liu X*. Acrylamide induces mitochondrial dysfunction

　　and apoptosis in BV-2 microglial cells. Free Radical Biology & Medicine, 2015, 84, 42-53.

　　(2) Wu W., Li Y., Wu Y., Zhang Y., Wang Z. and Liu X*. Lutein suppresses inflammatory responses through Nrf2

　　activation and NF-κB inactivation in lipopolysaccharide-stimulated BV-2 microglia. Molecular Nutrition & Food

　　Research, 2015, In press.

　　(3) Liu Q., Wang Y., Xiao C., Wu W. and Liu X*. metabolism of chicoric acid by rat liver microsomes and

　　bioactivity comparisons of chicoric acid and its metabolites. Food & Function, 2015, In press.

　　(4) Yuan L., Wei S., Wang J. and Liu X*. Isoorientin Induces Apoptosis and Autophagy Simultaneously by Reactive

　　Oxygen Species (ROS)-Related p53, PI3K/Akt, JNK, and p38 Signaling Pathways in HepG2 Cancer Cells. Journal of

　　Agricultural and Food Chemistry, 2014, 62, 5390-5400.

　　(5) Wang J., Yuan L., Xiao H., Wang C., Xiao C., Wang Y. and Liu X*. A novel mechanism for momordin Ic-induced

　　HepG2 apoptosis: involvement of PI3K- and MAPK-dependent PPARγ activation. Food & Function, 2014, 5, 859-868.

　　(6) Wang Y., Liu Y., Xiao C., Liu L., Hao M., Wang J. and Liu X*. Simultaneous determination of 15 phenolic

　　constituents of Chinese black rice wine by HPLC-MS/MS with SPE. Journal of Food Science, 2014, 79, 1100-1105.

　　(7)Yuan L., Wang Y., Wang J., Xiao H. and Liu X*. Additive effect of zinc oxide nanoparticles and isoorientin

　　on apoptosis in human hepatoma cell line. Toxicology letters, 2014, 225, 294-304

　　(8) Wu W., Wang X., Xiang Q., Meng X., Peng Y., Du N., Liu Z., Sun Q., Wang C. and Liu X*. Astaxanthin

　　alleviates brain aging in rats by attenuating oxidative stress and increasing BDNF levels. Food & Function, 2014,

　　5, 158-166.

　　(9) Yuan L., Wu. Y., Ren X., Liu Q., Wang J. and Liu X*. Isoorientin attenuates lipopolysaccharide-induced

　　pro-inflammatory responses through down-regulation of ROS-related MAPK/NF-κB signaling pathway in BV-2 microglia.

　　Molecular and Cellular Biochemistry, 2014, 386, 153-165

　　(10) Xiang Q., Liu Q., Xu L., Qiao Y., Wang Y. and Liu X*. Carnosic acid protects biomolecules from free

　　radical-mediated oxidative damage in vitro. Food Science and Biotechnology, 2013, 22, 1381-1388

　　(11) Xiao H., Xie G., Wang J., Hou X., Wang X., Wu W. and Liu X*. Chicoric acid prevents obesity by attenuating

　　hepatic steatosis, in?ammation and oxidative stress in high-fat diet-fed mice. Food Research International, 2013,

　　54, 345-353

　　(12) Liu Z., Xiang Q., Du L., Song G., Wang Y. and Liu X*. The interaction of sesamol with DNA and cytotoxicity,

　　apoptosis, and localization in HepG2 cells. Food Chemistry, 2013, 141, 289-296

　　(13) Wang J, Yuan L, Xiao H, Xiao C, Wang Y, and Liu X*. Momordin Ic induces HepG2 cell apoptosis through MAPK

　　and PI3K/Akt-mediated mitochondrial pathways. Apoptosis, 2013, 18, 751-765 (IF: 4.788)

　　(14) Xiang Q., Wang Y., Wu W., Meng X., Qiao Y., Xu L. and Liu X*. Carnosic acid protects against

　　ROS/RNS-induced protein damage and upregulates HO-1 expression in RAW264.7. Journal of Functional Foods, 2013, 5,

　　362-369

　　(15) Xiao H., Wang J., Yuan L., Xiao C., Wang Y. and Liu X*. Chicoric acid induces apoptosis in 3T3-L1

　　preadipocytes through ROS-mediated PI3K/Akt and MAPK signaling pathways. Journal of Agricultural and Food

　　Chemistry. 2013, 61, 1509-1520.

　　(16) Yuan L., Wang J., Xiao H., Wu W., Wang Y. and Liu X*. MAPK signaling pathways regulate mitochondrial-

　　mediated apoptosis induced by isoorientin in human hepatoblastoma cancer cells. Food and Chemical Toxicology,

　　2013, 53, 62-68.

　　(17) Xiang Q., Liu Z., Wang Y., Xiao H., Wu W., Xiao C. and Liu X*. Carnosic acid attenuates lipopolysaccharide-

　　induced liver injury in rats via fortifying cellular antioxidant defense system. Food and Chemical Toxicology,

　　2013, 53, 1-9.

　　(18) Qiao Y., Xiang Q., Yuan L., Xu L., Liu Z. and Liu X*. Herbacetin induce apoptosis in HepG2 Cells :

　　Involvements of ROS and PI3K/Akt. Food and Chemical Toxicology, 2013, 51, 426-433.

　　(19) Yuan L., Wang J., Xiao H., Xiao C., Wang Y. and Liu X*. Isoorientin induces apoptosis through disordering

　　mitochondrial function and inhibition of PI3K/Akt signaling pathway in HepG2 cancer cells. Toxicology and Applied

　　Pharmacology, 2012, 265, 83-92

　　(20) Xiao H., Wang Y., Xiang Q., Xiao C., Yuan L., Liu Z. and Liu X*. Novel physiological properties of ethanol

　　extracts from Eremurus chinensis Fedtsch. roots: in vitro antioxidant and anticancer activities. Food & Function,

　　2012, 3, 1310-1318.

　　(21) Xiang Q., Xiao H., Gao S., Wen M., Jia G., Ren X. and Liu X*. In vitro antioxidant properties of Rosa

　　roxburghii aqueous extracts. Australian Journal of Crop Science, 2012, 6, 854–860.

　　(22) Liu, X., Shibata, T., Hisaka, S. and Osawa, T. Astaxanthin inhibits reactive oxygen species-mediated

　　cellular toxicity in dopaminergic SH-SY5Y cells via mitochondria-targeted protective mechanism. Brain Research,

　　2009, 1254, 18-27.

　　(23) Liu, X., Yamada, N., Shibata, T., Maruyama, W. and Osawa, T., Formation of dopamine adducts derived from

　　brain polyunsaturated fatty acid: Mechanism for Parkinson’s disease. Journal of Biological Chemistry, 2008,

　　283, 34887-34895.

　　(24) Liu, X., Shibata, T., Hisaka, S., Kawai, Y. and Osawa, T. DHA hydroperoxides as a potential inducer of

　　neuronal cell death: A mitochondrial dysfunction- mediated pathway. Journal of Clinical Biochemistry and

　　Nutrition, 2008, 43, 26-33.

　　(25) Liu, X., and Osawa, T., Cis astaxanthin and especially 9-cis astaxanthin exhibits a higher antioxidant

　　activity in vitro compared to the all-trans isomer. Biochemical and Biophysical Research Communications,

　　2007, 357, 187-93.

　　(26) Liu, X., and Osawa, T., Astaxanthin Protects Neuronal Cells against Oxidative Damage and Is a Potent

　　Candidate for Brain Food. Forum of Nutrition, 2009, 61, 129-135.

　　(27) Liu, X., Yamada, N. and Osawa, T., Assessing the neuroprotective effect of antioxidative food factors by

　　application of lipid-derived dopamine modification adducts. Methods in Molecular Biology, 2009, 580, 143-152

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