近年来主持的科研项目

 

　　1.  代谢组学数据的多层次融合和模型评价方法研究（国家自然科学基金地区基金项目，批准号：21465016；49万元；2015-2018）

 

　　2. 基于代谢组学的2型糖尿病高危人群风险评估方法研究（国家自然科学基金青年项目，批准号：21105129；25万元；2012-2014）

 

　　3.  代谢组学数据的多层次融合和模型评价方法研究（国家自然科学基金地区基金项目，批准号：21465016；49万元；2015-2018）

 

　　4.  鼻咽癌治疗过程的血清代谢组学研究（863项目“靶向EBV-LMP1的脱氧核酶技术提高鼻咽癌放疗敏感性的深入研究”子课题；批准号：2009AA02Z403；8万元；2010-2012)

 

　　5.  基于系统生物学的中药现代化基础研究（科技部国际科技合作项目；批准号：2007DFA40680；第二负责人；190万元；2008-2010）

 

　　6.  基于代谢组学的鼻咽癌诊断与疗效跟踪研究（中国博士后科学基金；批准号：20080440181； 5万元；2009-2011）

 

　　7.  鼻咽癌特异性代谢标记物筛选及其代谢网络研究（中国博士后科学基金特别资助；批准号：200902481；10万元；2010-2011）

 

　　近年来发表的部分学术论文

 

　　1. Lunzhao Yi, Shuting Shi, Yang Wang, Wei Huang, Zi-an Xia, Zhihua Xing, WeijunPeng*, Zhe Wang*. Serum metabolic profiling reveals altered metabolic pathways in patients with post-traumatic cognitive impairments. Scientific Reports, 2016, 6:21320

 

　　2. Lunzhao Yi*, Naiping Dong, Yonghuan Yun, Baichuan Deng, DabingRen, Shao Liu, Yizeng Liang. Chemometric methods in data processing of mass spectrometry-based metabolomics: A review. Analytica Chimica Acta, 2016, 914:17-34

 

　　3. Dabing Ren, Binsong Han, Zhongquan Xin, Wenbin Liu, Shasha Ma, Yizeng Liang, Lunzhao Yi*. Computation-aided separation of seven components from Spirodela polyrrhiza (L.) via counter-current chromatography. Separation and Purification Technology, 2016, 165:160-165

 

　　4. Yonghuan Yun, Fu Liang, Baichuan Deng, Guangbi Lai, Carlos M. Vicente Goncalves,Hongmei Lu, Jun Yan, Xin Huang, Lunzhao Yi*, Yizeng Liang*. Informative metabolites identification by variable importance analysis based on random variable combination. metabolomics，2015, 11(6): 1539-1551

 

　　5. Lunzhao Yi*, Naiping Dong, Shao Liu, Zhibiao Yi, Yi Zhang*. Chemical features of PericarpiumCitriReticulatae and PericarpiumCitriReticulataeViride revealed by GC-MS metabolomics analysis. Food Chemistry, 2015, 186:192-199

 

　　6. DabingRen, Lunzhao Yi*, Yanhua Qin, Yonghuan Yun, Baichuan Deng, Hongmei Lu, Xiaoqing Chen, Yizeng Liang*. Systematic and practical solvent system selection strategy based on the nonrandom two-liquid segment activity coefficient model for real-life counter-current chromatography separation. Journal of Chromatography A, 2015, 1393: 47-56

 

　　7. Lunzhao Yi, Chenchao Song, Zheyu Hu, Lifang Yang, Lanbo Xiao, Bin Yi, Wuzhong Jiang, Ya Cao*, Lunquan Sun*. A metabolic discrimination model for nasopharyngeal carcinoma and its potential role in the therapeutic evaluation of radiotherapy. metabolomics. 2014,10(4):697-708

 

　　8. Zhifang Sun, Qiyu Huang, Ting He, Zhengyuan Li, Yi Zhang*, Lunzhao Yi*. Multistimuli Responsive Supramolecular Gels: Design Rationale, Recent Advances and Perspectives. ChemPhysChem. 2014. 15,2421-2430. （特邀评论，封面文章）

 

　　9. Lunzhao Yi*, Naiping Dong, Shuting Shi, Baichuan Deng, Yonghuan Yun, Zhibiao Yi, Yi Zhang. metabolomic identification of novel biomarkers of nasopharyngeal carcinoma. RSC Advances, 2014,4, 59094-59101

 

　　10. Nai-ping Dong,Yi-Zeng Liang*,Qing-song Xu, Daniel K. W. Mok, Lun-zhao Yi, Hong-mei Lu, Min He, Wei Fan. Prediction of Peptide Fragment Ion Mass Spectra by Data Mining Techniques. Analytical chemistry. 2014,86, 7446？7454

 

　　11. Bai-chuan Deng, Yong-huan Yun, Yi-zeng Liang*, Lun-zhao Yi. A novel variable selection approach that iteratively optimizes variable space using weighted binary matrix sampling Analyst, 2014, 139, 4836-4845 (2014年热点文章)

 

　　12. Zhenzhu Zhang, Ting He, Mengying Yuan, RujuanShen, Liu Deng, Lunzhao Yi, Zhifang Sun*, Yi Zhang*. In situ synthesis of Ag/amino acid biopolymer hydrogels as mouldable wound dressing. Chemical Communication, 2015, 51(87): 15862-15865

　　承担课程

 

　　本科课程: 《食品质量安全检测技术》

 

　　研究生课程：《现代仪器分析》、《食品安全研究进展》