§184.1250 长枝木霉属产生的纤维素酶制剂(Cellulase enzyme preparation derived from Trichoderma longibrachiatum)

　　（a� Cellulase enzyme preparation is derived from a nonpathogenic, nontoxicogenic strain of Trichoderma longibrachiatum （formerly T. reesei �? The enzyme, cellulase, catalyzes the endohydrolysis of 1,4-beta-glycosidic linkages in cellulose. It is obtained from the culture filtrate resulting from a pure culture fermentation process.

　　（b� The ingredient meets the general and additional requirements for enzyme preparations in the monograph specifications on enzyme preparations in the ��Food Chemicals Codex,�� 4th ed. �?996�? pp. 129 to 134, which is incorporated by reference in accordance with 5 U.S.C. 552（a� and 1 CFR part 51. Copies are available from the National Academy Press, 2101 Constitution Ave. NW., Box 285, Washington, DC 20055 （Internethttp://www.nap.edu�? or may be examined at the Center for Food Safety and Applied Nutrition's Library, 5100 Paint Branch Pkwy., College Park, MD 20740, or at the National Archives and Records Administration （NARA�? For information on the availability of this material at NARA, call 202�C741�C6030, or go to:http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html.

　　（c� In accordance with��184.1（b）（1�? the ingredient is used in food with no limitation other thancurrent good manufacturing practice. The affirmation of this ingredient as generally recognized as safe （GRAS� as a direct human food ingredient is based upon the following current good manufacturing practice conditions of use:

　　�?� The ingredient is used in food as an enzyme as defined in��170.3（o）（9� of this chapter for the breakdown of cellulose.

　　�?� The ingredient is used in food at levels not to exceed current good manufacturing practice.

　　[64 FR 28361, May 26, 1999]