欧盟评估地衣芽孢杆菌DSM 19670生产的丝氨酸蛋白酶作为鸡育肥饲料添加剂的安全性和有效性_安全事件解读_专业解读_食品安全合规服务_食品伙伴罐�/title>

　　 食品伙伴网讯2021�?�?日，据欧盟食品安全局（EFSA）消息，应欧盟委员会要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组就地衣芽孢杆菌DSM 19670生产的丝氨酸蛋白酶（serine protease ）作为鸡育肥饲料添加剂的安全性和有效性发表科学意见�

　　经过评估，专家小组得出结论，该添加剂对鸡育肥是安全的。在没有数据的情况下，无法得出有关皮肤致敏潜力的结论。当添加剂使用水平为15,000 PROT/kg饲料对鸡育肥有效。部分原文报道如下：

　　Ronozyme ?ProAct is the trade name of the feed additive under assessment and co ntains serine protease produced by a genetically modified strain of Bacillus licheniformis. Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Ronozyme? ProAct when used as a zootechnical additive for chickens for fattening. The additive is available in coated thermotolerant granulated and liquid forms (Ronozyme ?ProAct CT/L). The production strain and its recombinant DNA were not detected in an intermediate co ncentrated product used to produce the final formulations. The final products do not trigger a safety co ncern with regard to the genetic modification. ba sed on the results obtained in a tolerance study in chickens for fattening and the data from a subchro nic oral toxicity study the FEEDAP Panel co ncluded that the additive is safe for chickens for fattening. The FEEDAP Panel co ncluded that the use of Ronozyme ?ProAct CT/L as a feed additive gives rise to no co ncern for co nsumers and for the environment. The additive, in either form, is not an eye irritant but should be co nsidered a skin irritant. In the absence of data, no co nclusions on the skin sensitisation potential can be reached. Owing to the proteinaceous nature of the active substance it should be co nsidered a respiratory sensitiser. The FEEDAP Panel also co ncluded that the additive has the potential to be efficacious at 15,000 PROT/kg compound feed for chickens for fattening.

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