食å“伙伴网讯2023å¹?2æœ?日,æ®æ¬§ç›Ÿé£Ÿå“安全局(EFSA)消æ¯ï¼Œæ¬§ç›Ÿè¥å…»ã€æ–°åž‹é£Ÿå“和食物过æ•æºï¼ˆNDAï¼‰ç ”ç©¶å°ç»„就乳酰-N-岩藻五糖I/2¡ä-岩藻糖基乳糖(LNFP-I/2¡¯-FL)混åˆç‰©ä½œä¸ºæ–°åž‹é£Ÿå“的安全性å‘表科å¦æ„è§ã€
  ç»è¿‡è¯„估,专家å°ç»„得出结论,在æ议的使用æ¡ä»¶ä¸‹ï¼ŒLNFP-I/2¡¯-FLæ··åˆç‰©ä½œä¸ºæ–°åž‹é£Ÿå“是安全的。部分原文报é“如下:
  Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on lacto-N-fucopentaose I (LNFP-I)/2¡ä-fucosyllactose (2¡¯-FL) mixture as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is mainly composed of the human-identical milk oligosaccharides (HiMO) LNFP-I and 2¡¯-FL, but it also co
ntains d-lactose, lacto-N-tetraose, difucosyllactose, 3-fucosyllactose, LNFP-I fructose isomer, 2¡ä-fucosyl-d-lactulose, l-fucose and 2¡ä-fucosyl-d-lactitol, and a small fraction of other related saccharides. The NF is produced by fermentation by a genetically modified strain (Escherichia coli K-12 DH1 MDO MP2173b) of E. coli K-12 DH1 (DSM 4235). The information provided on the identity, manufacturing process, composition and specifications of the NF does not raise safety concerns. The applicant intends to add the NF in a variety of foods, including infant formula (IF) and follow-on formula, foods for infants and toddlers, foods for special medical purposes and food supplements (FS). The target population is the general population. The anticipated daily intake of LNFP-I from use in IF is similar to the estimated natural mean highest daily intake in breastfed infants. Overall, the anticipated daily intake of LNFP-I from the NF as a food ingredient at the maximum proposed use levels is unlikely to exceed the intake level of breastfed infants on a body weight basis. The intake in breastfed infants on a body weight basis is expected to be safe also for other population groups. The anticipated 2¡¯-FL intake is generally rather low. The use of the NF in FS is not intended if other foods with added NF compo
nents or human milk (for infants and young children) are co
nsumed on the same day. The Panel co
ncludes that the NF, a mixture of LNFP-I and 2¡¯-FL, is safe under the proposed co
nditions of use.
  
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